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10.1074/jbc.270.50.29705 9 BlikstadC.ShokeerA.KurtovicS.MannervikB

Since the high metabolic needs of KRAS - or BRAF -mutated cancer rely mostly on glycolysis, these mechanistic insights may explain why high-dose vitamin C provides strong benefits in these tumors

Icariin and icaritin induce apoptosis in multiple cancers, such as breast, liver, ovarian, lung, colon, cervical, neuroblastoma and NK/T-cell lymphoma by enhancing pro-apoptotic proteins and reducing anti-apoptotic proteins [697, 708, 735,736,737,738,739,740,741,742,743,744,745]

Metabolic Needs of the Kidney Graft Undergoing Normothermic Machine Perfusion

(2011) 6:e22323

Additionally, mice and rats have been observed to transfer AX to various tissues, including adipose tissue, liver, skeletal muscle, brain, and others [250,326]