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Such a defined binding site could also provide a basis for allosteric modulation of transporter function in a diverse array of settings

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This circuit disruption results from loss of the finely tuned dopamine delivery to the striatum via long-distance axonal projections

doi: 10.3389/fimmu.2025.1549865 Received 22 December 2024 Accepted 14 July 2025 Published 30 July 2025 Volume 16 - 2025 Edited by Mariusz Cyco, Medical University of Silesia, Poland Reviewed by Cuncai Guo, Washington University in St

First, the increased concentration of H 2 O 2 inhibits the enzymes MS and BHMT and activates the enzymes CBS and GCS [25, 26]

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