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Its proposed mechanisms involve multiple cytoprotective pathways including upregulation of VEGF and growth factors promoting angiogenesis, modulation of the nitric oxide system, activation of the FAK-paxillin pathway for cell migration and tissue repair, interaction with the gut-brain axis affecting dopaminergic and serotonergic systems, and gastroprotective effects against NSAID and alcohol-induced mucosal damage

LipofectAMINETM 2000 (Invitrogen) according to the manufacturer's protocol

Treatment with vimentin and HMGB1 concerning organ transplantation can lead to the development of trained immunity (81)

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[DOI] [PMC free article] [PubMed] [Google Scholar] UNDP (United Nations Development Programme)

Visualization of differentially expressed genes was done with EnhancedVolcano 130