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The onset of action can vary based on individual factors such as metabolism and rectal conditions

This design reflects a translational nanoplatform strategy emphasizing efficient skin barrier penetration, modulation of the local immune microenvironment, and precise drug release, thereby providing an innovative approach for chronic dermatological disease management [76]

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People with gastrointestinal diseases affecting nutrient absorption may require high doses of vitamin B12 supplements

This intensive approach suits short-term focused treatment phases

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