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Riluzole slightly extends survival by reducing glutamate toxicity, whereas edaravone may slow functional decline in selective early-stage patients

Sirtuins, particularly SIRT1, need NAD+ as a cofactor for protein deacetylation

Reactive oxygen species in autoimmune cells: function, differentiation, and metabolism

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Several limitations and challenges must be addressed for the clinical translation of UA as follows

Selective mitochondrial glutathione depletion by ethanol enhances acetaminophen toxicity in rat liver