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The cortex is thinner than the controls due to reduced proliferation

The mTORC1 complex is activated by amino acids (especially leucine), growth factors, nutrients, and oxidative stress, and its activation is associated with augmented cell survival because it results in increased protein synthesis, initiation of lipid biosynthesis, and diminished autophagy [316]

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As a further control for the conversion of NADP + to NADPH, we simultaneously detected an increase in NADPH autofluorescence after initiating the reaction