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We searched ClinicalKey, ClinicalTrials.gov, Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, MEDLINE, PubMed and ScienceDirect for relevant studies published from 1 January 2000 to 30 April 2020

Daniels, Darren Robertson, Janeli Sarv, Jos Snchez, Debra Carter, Lutz Jermutus, Benjamin Challis, Arun J

Perturbations in a wide range of neurochemical systems produced by the chronic presence of alcohol contribute to significant changes in neural activity (neuroadaptations) that ultimately compromise the functional integrity of the brain

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Recent studies have implicated TMAO, an intestinal microbiota-dependent metabolite, in the pathogenesis and progression of IBD through its role in immune regulation