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Conclusions This study successfully demonstrated that strategic chemical modifications to glutathione (GSH) can significantly enhance its oral bioavailability, overcoming the key limitations associated with its native form

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Cell size measurements and mitochondrial mass quantification protocol Live cell size measurements were performed by flow cytometry, using single-cell cytograms to identify and exclude doublets or cell aggregates

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Among lncRNAs, MALAT1, lincRNA-p21, TUG1, and H19 have been identified as key modulators: MALAT1 associates with UVB-induced senescence and photoaging in dermal fibroblasts and may have analogous roles in melanocytes, while lincRNA-p21 mediates p53-dependent apoptosis and cell cycle arrest to prevent malignant transformation 107