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Furthermore, ROS can induce DNA damage in sperm, which can also contribute to structural deformities

no signal of heart valve damage or tachycardia beyond what is expected from weight loss)

7 In fact, xCT is considered to be the main transporter of cystine in cancer (Table 1) 25,26,27 and its expression is controlled by nuclear factor erythroid 2-related factor 2 (NRF2), a master regulator of the cellular redox state, 28 highlighting the importance of xCT in an oxidative stress-resistant cancer cell phenotype

Germline Cancer Risk Profiles of Young-Onset Colorectal Cancer Patients: Findings from a Prospective Universal Germline Testing and Tele-Genetics Program

doi: 10.1101/cshperspect.a032359 164

10.1021/acsnano.2c08774 185 ThryC.AmigorenaS.RaposoG.ClaytonA
