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The synthesis of neurotransmitters by probiotics may influence the physiopathology of AD by modulating the A metabolism, Tau pathology, and inflammation

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78 Njoo MD, Vodegel RM, Westerhof W

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TLR4 activation triggers various pro-inflammatory processes in microglia, including an augmented production of ROS [88]

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showed that the altered function of Mn-dependent glycosyltransferase led to colon barrier dysfunction and inert inflammation in an SLC39A8 A391T mouse model, suggesting that reduced intestinal barrier integrity is the mechanism underlying this pleiotropic effect 45

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