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In contrast, there were increases in expression profiles related to fatty acid oxidation with decreases in glycolysis-related profiles

Pancreatic cells are more sensitive to cytotoxic stress than several other cells due to the expression of very low levels of antioxidant enzymes

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Metabolic profiling identified metabolites up-regulated by 5-oxp that are involved in the metabolic pathways of carbon assimilation in photosynthesis, glycolysis and the tricarboxylic acid cycle of respiration, proteinogenic amino acid metabolism, glutathione metabolism, and nucleotide metabolism for DNA or RNA synthesis and ATP generation