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Spautin-1 Based on 24 publication(s) in Google Scholar Spautin-1 is a specific and potent autophagy inhibitor which inhibits ubiquitin-specific peptidases, USP10 and USP13 with IC 50 s of 0.6-0.7 M
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The existing evidence base comes from preclinical (animal) studies conducted primarily at Washington State University, where the compound was developed and patented for potential use in Alzheimer's disease
