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Large double-blind, placebo-controlled trials are needed to understand whether folic acid supplementation late in life might help decrease age-related cognitive impairments or the risk of Alzheimers disease and other dementias

This makes it appealing for long-term optimization strategies

Reliability of hormonal levels for assessing the hypothalamicpituitaryadrenocortical system in clinical pharmacology

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Together, our study establishes lipoprotein uptake as a critical anti-ferroptotic mechanism in cancer and implicates GAG biosynthesis as a therapeutic target