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This could make it harder for the body to regulate weight

In severe cases, a vitamin B12 deficiency can lead to neurological damage and even death

Having an autoimmune disease : Some autoimmune diseases can damage the stomach lining (including pernicious anemia) where intrinsic factor is produced

The good news is that B12 is one of the safest vitamins, but there are a few things to know about high-dose supplements and when theyre actually necessary

SIRT1 is part of a family of proteins called sirtuins, known as longevity genes. It uses NAD+ as a fuel source to repair DNA, reduce inflammation, and improve stress resistance

Ive found that patients who experience these side effects simply reduce the dosing and frequency of their B12 the symptoms usually resolve