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Elevated intracellular GSH levels blocked bortezomib-induced nuclear factor erythroid 2-related factor 2 (NFE2L2, NRF2)-associated stress responses, including upregulation of the xCT subunit of the Xc- cystine-glutamate antiporter

This leads to decreased inflammation by modulating NF-B signaling, as higher NAD+ supports sirtuin-mediated deacetylation of pro-inflammatory factors

European Archives of Psychiatry and Clinical Neuroscience

In addition to its antioxidant properties, glutathione is also involved in essential detoxification processes

A randomized controlled trial of the efficacy and safety of a fixed triple combination (fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%) compared with hydroquinone 4% cream in Asian patients with moderate to severe melasma

Beside adipokines, other hormones are also involved in the maintenance of a healthy metabolism