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They may need more blood vessel support or lets say they have a B12 deficiency

One thing that puzzles me, is why you think you need an injection of B12 daily

In particular, myo-inositol modulated oral glucose tolerance tests (OGTTs) in polycystic ovary syndrome (PCOS) without familial diabetes, ALA increased insulin response to OGTT and metabolic parameters in all patients, and the combination of myo-inositol + ALA improved hormonal and metabolic aspects and insulin response to OGTT in all patients

Skin quality, body composition, recovery, and wellness-related changes may become more noticeable for some patients

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Some research suggests that glutathione may also influence melanin production in the skin