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While ars4 was shown to be a phytochrome A ( phyA ) mutant (Sung et al., 2007), ars5 is affected in a component of the 26S proteasome (Sung et al., 2009)

[11] It is less preferred than hydroxocobalamin for treating vitamin B 12 deficiency because it has a slightly lower bioavailability

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Most standard supplements are broken down by stomach acid or filtered out by the liver before they ever reach your cells

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