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Standard / Gradual Approach There is no titration schedule for Dihexa in humans, because human absorption, metabolism, and the therapeutic window are simply unknown

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doi: 10.1016/0167-5273(95)02423-T

Through the estrogen binding to its receptor, tyrosinase and microphthalmia transcription factor (MITF) can be activated and therefore melanin would be increased (Lee, 2015)

In the same study, measurements of inflammatory cytokines were performed

There are risks to the mother and fetus associated with untreated hypothyroidism in pregnancy