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Recently, it has been reported that a few sets of metabolites, especially amino acids like arginine, tryptophan and asparagine are very important for both host as well as bacteria, for which they compete and form a metabolic interface [2]

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Diverse phytochemical classes, including polyphenols, terpenoids, and alkaloids, converge on key regulatory nodes such as nuclear factor erythroid 2-related factor 2 (Nrf2), NF-B, and PI3K/Akt pathways, which collectively regulate oxidative stress, inflammation, endothelial function, and cell survival (Syed et al., 2023)