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For example, selenium-deficient animals and human cell lines exhibit reduced transcription of selenoproteins such as GPX1 , DIO s, SELENOI , and SELENOW 55,56,57

10.1038/s41575-020-00372-7 47 KumadaH

A meta-analysis of controlled trials

Current senolytic agents are primarily employed in cancer therapies, such as doxorubicin, trametinib, and cell cycle-targeting drugs like palbociclib (Lea et al., 2022

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