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Full text: Figueroa-Mndez, R., & Rivas-Arancibia, S

For LNPs conjugated to active targeting moieties, such as specific antibodies, affinity-based pull-down isolation methods have emerged as a promising approach to separate protein-coated LNPs from a biological fluid, however this methodology still risks the co-isolation of endogenous EVs due to the potential for the targeting antibodies to dissociate from the LNPs and embed within the contaminating EVs 51,52

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