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FIGURE 1 3.2 Selenenylsulfide of the non-reduced TrxR1 reacted with DTNB Because three-dimensional structures of the non-reduced TrxR1 are available (Supplementary Figure S1, among 14 Cys residues and 1 Sec residue per subunit, Cys189, Cys296, Cys497 and Sec498 are closer to the surface than the others