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The rate of pancreatic secretion is decreased, which means decreased amylase, trypsin, lipase, sodium bicarbonate, and other enzymes

This gives your body time to respond without overwhelming it

This essential nutrient plays a key role in transporting fatty acids into the cells' mitochondria, where they can be converted into energy

Examples include: Diagnostic contrast administration Certain test substances Documentation must support the diagnostic purpose

You should contact your GP if: Your B12 level is significantly elevated (markedly above your local laboratory's reference range) without obvious explanation such as supplementation You have persistent elevation on repeat testing You experience unexplained symptoms such as unintentional weight loss, persistent fatigue, night sweats, fever, or abdominal discomfort You notice unusual bruising, bleeding, or enlarged lymph nodes You have jaundice (yellowing of skin or eyes) or other signs of liver disease You have a history of liver disease, kidney disease, or blood disorders Immediate medical attention (contact NHS 111 or attend A&E) is warranted if you experience severe symptoms such as significant bleeding, severe abdominal pain, confusion, or signs of acute illness, though these would rarely be directly related to elevated B12 itself

If they don't, it can be overwhelming trying to figure out what to do next