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Activity Restrictions : Its crucial to avoid strenuous physical activity and heavy lifting during the initial recovery phase
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In parallel, studies using human iPSC-derived brain organoids reveal that esketamine induces rapid, concentration-dependent metabolic reprogramming, characterized by transient suppression of OXPHOS and glycolysis, accompanied by altered intracellular energy status, Ca signaling, and neuronal excitability [138]
Active metabolite (MND) has a half-life of 9-10 hours
