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Woolston CM, Al-Attar A, Storr SJ, Ellis IO, Morgan DA, Martin SG

Inhibiting interleukin 36 receptor signaling reduces fibrosis in mice with chronic intestinal inflammation

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For patients diagnosed with a vitamin B12 deficiencyespecially when caused by problems with absorption in the digestive tract (such as pernicious anemia, certain gastrointestinal conditions, or after specific surgeries)oral supplements may not be effective

2 Additionally, contrary to previous understanding, symptoms of withdrawal are often severe, and can include increased suicidal ideation