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& Bauer, S
doi: 10.1007/s12011-019-1654-5 94
Tirzepatide is a once-weekly injectable medication, FDA-approved under the brand name Mounjaro to treat type 2 diabetes and FDA-approved under the brand name Zepbound for weight loss
This excessive phosphorylation of EGFR with a disrupted dimer structure leads to the development of TKI resistance in ROS-exposed EGFR-sensitive NSCLC cell lines
Individuals with Lebers disease, a hereditary optic nerve disorder, should avoid this medication due to the risk of exacerbating the condition
However, some meta-analyses report weak or null associations in non-Asian populations, suggesting gene-environment interactions require further elucidation (Dou et al., 2013
