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2b), resulted in no significant differences in GST activity (Extended data Fig

In agreement with this, the ability of PA to protect cells against oxidative stress has been associated with inhibited ROS generation, increased GSH levels, and decreased lipid peroxidation (MDA), as shown in several studies ( An increased ROS level can directly or indirectly control the SIRT-1 enzyme ( SIRT-1 has a crucial role in modulating multiple physiological processes

In summary, exercise modulates ferroptosis through multiple interconnected molecular pathways

Given that XKR8 is a caspase-3-activated phospholipid scramblase, we next investigated whether caspase-3 is involved in PMA-induced NET formation

LPS, a component released into the intestinal lumen upon bacterial death and lysis, disrupts the host immune and coagulation systems (22)