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and (3) glutathione S-transferases (GST) to conjugate GSH with endogenous substances (e.g., estrogens), exogenous electrophiles (e.g., arene oxides, unsaturated carbonyls, organic halides), and diverse xenobiotics

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Also in hypertension, a deficiency of BH 4 decreases NO synthesis and increases superoxide production, and reduced availability of BH 4 may contribute to the development and maintenance of hypertension

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The safety profile remained consistent across different dose levels, administration routes, and treatment durations

Therapeutic effect of adjunctive N-acetyl cysteine (Nac) on symptoms of chronic schizophrenia: A double-blind, randomized clinical trial