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Rheumatology (Oxford) 56:934939

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Thus, it is possible that motor neurons have the potential to regulate their own output directly via feedback from the muscle

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Animal experimental evidence Osteoclast precursor (RAW264.7) experiment: AOD 9604 significantly inhibited RANKL induced osteoclast formation, reduced the number of TRAP positive multinucleated cells, and decreased bone resorption pit formation