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Proinflammatory properties of glutathione peroxidase-4 Notably, the 718C allele of the GPX4 gene was found to be associated with the increased levels of lymphocyte lipoxygenase products implying that the polymorphism can modulate inflammatory processes through the regulation of the biosynthesis of leukotrienes, thromboxanes and prostaglandins

[DOI] [PMC free article] [PubMed] [Google Scholar] 103.Hsieh M.J., Lee C.H., Chueh H.Y., Chang G.J., Huang H.Y., Lin Y., Pang J.S

Jaldin-Fincati, J

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Overexpression of the mitochondrial T3 receptor (p43) has also been shown to induce lipid peroxidation and lead to muscle atrophy

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