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Inactivation of these enzymes correlated with increased hydrogen peroxide, decreased ATP level, accumulation of lipid peroxides such as malondialdehyde (MDAL), and triglyceride fat accumulation, respectively [44]

Glutationa peroxidase-1 em sade e doena: dos mecanismos moleculares s oportunidades teraputicas

Meldgaard T, Olesen SS, Farmer AD, Krogh K, Wendel AA, Brock B, Drewes AM, Brock C (2018) Diabetic enteropathy: from molecule to mechanism-based treatment

15 , 16 moreover, this also correlated positively with the degree of emphysema and modified Medical Research Council (mMRC) dyspnea score, while being negatively correlated with partial pressure of arterial oxygen PaO 2 , diffusing capacity of the lungs for carbon monoxide (DLCO), 6 min walk test and maximum exercise work load