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Intramuscular means the medicine is injected into muscle

Long-term supplementation should be monitored by a physician

10.1007/s11901-006-0019-7 12 CastelliM

These include peripheral neuropathy (tingling, numbness, or burning sensations in the hands and feet), difficulty walking, balance problems, and memory impairment

10.1074/jbc.R113.458810 23 GreenR

MOTS-c is a mitochondrial-derived peptide that activates AMPK through direct mitochondrial signaling and nuclear translocation under metabolic stress, whereas metformin activates AMPK indirectly by inhibiting Complex I of the mitochondrial electron transport chain, and AICAR mimics AMP to trick the cell into AMPK activation