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Moreover, the TRPV5-mediated renal calcium reabsorption is dependent on FGF-23 and its co-receptor (soluble -Klotho) [86, 87]

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The PI3K/AKT pathway is an important regulator of cell cycle progression

Furthermore, it aids in activating certain enzymes, which are proteins that accelerate biochemical reactions in the body

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Since TZDs have fallen out of use in recent years due to significant side effects, efforts are ongoing to identify natural product partial agonists of PPAR to combat metabolic syndrome (5760)
