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For example, a 10mg vial with 1mL of water should always produce 10,000mcg/mL

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Untreated B12 deficiency causes peripheral neuropathy (tingling, numbness, balance issues) and, in severe cases, cognitive decline

[124] Other causes of B 12 malabsorption include bariatric surgery, pancreatic insufficiency, obstructive jaundice, tropical sprue, celiac disease, inherited intrinsic factor deficiency, and radiation enteritis affecting the distal ileum

Talaei A, Siavash M, Majidi H, et al

undertook a double blind RCT in which a population with degenerative orthopaedic alteration with neural compression were randomised to a treatment arm of either nucleosides and B12 combination of cytidine monophosphate disodium (CMP) 2.5 mg, uridine triphosphate trisodium (UTP) 1.5 mg and hydroxocobalamin 1000 g orally ( n = 200) or a B12 only regimen of hydroxocobalamin 1.0 mg orally ( n = 200)