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Glutathione levels naturally decline because the body depends on them every day to handle stress and maintain balance

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Collectively, these findings highlight the metabolic interdependence of glutamine and cystine in TNBC, providing mechanistic insights into potential metabolic-targeted and dietary interventions for TNBC therapy.

In this review, we first delineate copper homeostasis at both cellular and systemic levels, clarifying coppers protumorigenic and antitumorigenic functions in cancer