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Consistent with these observations, a major reduction in intracellular glutathione levels was observed in PBMC lysates from COVID-19 patients compared to HCs ( Figure 4I ), suggesting an impaired intracellular host antioxidant response to control oxidative stress responses and ultimately lipid peroxidation

In addition, UDCA avoids efficiently the enhancement in LC3II protein expression and in the number of AVOs in enterocytes caused by NaDOC, which means that UDCA attenuates the biomarkers of autophagy[22]

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Aspergillus flavipes L-methionine -lyase--cyclodextrin conjugates with improved stability, catalytic efficiency and anticancer activity

Ultrafine carbon black induces glutamate and ATP release by activating connexin and pannexin hemichannels in cultured astrocytes

injectable use remains investigational