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These substances can combine with proteins to form acetaldehyde adducts, triggering immune responses and exacerbating inflammation and fibrosis in ALD patients (Michalak et al., 2021)

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[DOI] [PubMed] [Google Scholar] 92.Homma K, Fujisawa T, Tsuburaya N, Yamaguchi N, Kadowaki H, Takeda K, et al

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Variations in its catalytic activity of P-450 3A4 are important in issues of bioavailability and drug-drug interactions [44]

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