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[122] [123] Phase II hepatic metabolism renders the metabolites water-soluble, which are excreted by the kidneys

[111] targeted N-to-B delivery of thyrotropin-releasing hormone (TRH)(a polypeptide used for treating suicidal patients), using fast degrading poly(sebacic anhydride) (PSA) NPs

Mitochondrial Resilience and Energy Homeostasis By stimulating AMPK and NRF2 pathways, MOTS-C peptide helps maintain mitochondrial function under stress

It shows distinct neuroprotective effects, as it improves nerve regeneration and brings synaptic transmutations and diminished neurotransmitters back to normal levels

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