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By consuming lipid hydroperoxides, GPX prevents their decomposition into secondary products like aldehydes (e.g., malondialdehyde, MDA) that can further damage cellular structures

5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis

PGC-1 activity is modulated by post-translational modifications such as phosphorylation, acetylation, and methylation, which can either enhance or inhibit its function
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Adjustments were made for individual traditional cardiac risk factors (age, gender, diabetes mellitus, systolic blood pressure, former or current cigarette smoking, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol), extent of CAD, left ventricular ejection fraction, history of MI, baseline medications (aspirin, statins, -blockers, and ACE inhibitors), and renal function by estimated creatinine clearance
