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Magnetic Resonance investigation into the mechanisms involved in the development of high-altitude cerebral edema

The FASEB Journal, 34(6), 80688081

doi: 10.1289/EHP6990 112 HuJLesseurCMiaoYManservisiFPanzacchiSMandrioliDet al

In glaucoma, the progressive degeneration of retinal ganglion cells (RGCs) represents the core pathological mechanism underlying vision loss

While serious side effects like allergic reactions are rare, its important to monitor for any unusual symptoms.

(1) We extend previous work showing disruption of PDH in activated macrophages 6,47 and of modifications of lipoate levels 46 , and we can reconsitute pyruvate oxidation with exogenous lipoate