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This pathway is the primary energy source for the heart and a major energy source for skeletal muscle during sustained activity

Although the definition of carnitine insufficiency in liver cirrhosis patients remains unclear, the symptoms of carnitine deficiency are thought to be muscle cramps, general fatigue, hepatic encephalopathy, and hyperammonemia in liver cirrhosis patients

doi: 10.3389/fphys.2021.702826 Received 30 April 2021 Accepted 24 June 2021 Published 20 July 2021 Volume 12 - 2021 Edited by Enrique Jaimovich, University of Chile, Chile Reviewed by Alexis Diaz, The University of Sydney, Australia

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Clinical applications of carnitine and its metabolites Acylcarnitines have been used for decades in early diagnosis of several inherited metabolic disorders in newborn babies