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The NAFLD activity scores (steatosis/inflammation/ballooning degeneration) were calculated using the clinical criteria outlined by Kleiner et al
He, P., et al., Liver fibrosis and hepatic stellate cells: Etiology, pathological hallmarks and therapeutic targets
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BCNU treatment significantly increased cellular GSSG levels without affecting GSH levels (Fig
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Thus, the -glutamyl cycle may be considered as a multi-organ cycle in which the synthetic part occurs in liver and the catabolic part occurs in kidney amongst other tissues
