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J Am Chem Soc 143:14161427
Reconstitution math for the 50 mg 5-Amino-1MQ vial BAC water added 1.0 mL Concentration 50.0 mg/mL 1 unit (U-100) equals 0.50 mg (500 mcg) BAC water added 2.0 mL Concentration 25.0 mg/mL 1 unit (U-100) equals 0.25 mg (250 mcg) BAC water added 3.0 mL Concentration 16.7 mg/mL 1 unit (U-100) equals 0.167 mg (167 mcg) Use 3.0 mL as the maximum BAC-water volume for this 50 mg vial format
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Peng et al (64) treated neural stem cells (NSCs) with BDNF siRNA, and found that imipramine (IM) increases the neuroprotective effects, suppresses the inflammatory process in NSCs via the modulation of the MAPK pathway and Bcl-2 cascades, indirectly evaluating the anti-inflammatory effect of BDNF
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occasional mild injection-site reactions may occur with subcutaneous administration
