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[7] Signs of an allergic reaction (such as rash, hives, or anaphylaxis) preclude further use

Metabolic Pathway of Thiopurine Drugs as a Target for Gut Microbiota Recently, the gut microbiota has often been referred to as the invisible organ due to its involvement in the modulation of the immune system, etiology of many diseases and metabolism of xenobiotics (Spanogiannopoulos et al., 2016)

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Lipid peroxidation products like HNE and 15d-PGJ 2 also induce GCLM although the signaling pathways appear to differ with pathological levels of HNE (Iles and Liu, 2005)

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