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Targeted Supplementation Evidence-based supplements may include: Vitamin D3 for immune and hormonal regulation Selenium and zinc for thyroid antibody reduction and hormone conversion Iron (when deficient) to aid thyroid hormone production Glutathione and antioxidants for detox support and immune modulation Adaptogens like ashwagandha and rhodiola to regulate stress response 4

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Functionally, CD44 interacts with the extracellular matrix, particularly HA, to activate Nanog through some key signaling pathways, such as the Wnt/-catenin, and PI3K/Akt (96), the targeted Nanog has been utilized as a mediator to enhance the expression of drug resistance genes

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It plays a significant role in protecting the lining of the gastrointestinal tract from damage, promoting healing, and encouraging blood vessel growth

Verbal communication was assessed by the Pre-school Language Scale- Fifth edition (PLS-5) and the Social Communication Questionnaire (SCQ)