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First, we treated mice with TAM-inducible deletion of Gpx4 in hepatocytes (referred to as Alb-creER T2 ;Gpx4 fl/fl mice) (Fig

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Hypoxia enhances glioma resistance to sulfasalazine-induced ferroptosis by upregulating SLC7A11 via PI3K/AKT/HIF-1 axis

Our results demonstrate that LDHB-K58R upregulates SLC7A11, a key cystine/glutamate antiporter that fuels GSH biosynthesis (Liu et al

Before a lactose-free diet is prescribed, such intolerance must be diagnosed and confirmed by a medical professional via the recognized methods

These advancements position microneedle technology as a transformative approach for delivering GLP-1 receptor agonists, offering the potential to improve therapeutic adherence, minimize systemic side effects, and support decentralized care models for diabetes management [43]
