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Another issue is the concomitant generation of Fe 2+ , a known prooxidant that can produce additional radicals, such as OH from H 2 O 2

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If you experience inadequate response after 1216 weeks at a therapeutic maintenance dose (typically 1015 mg weekly) despite good adherence and lifestyle modifications, consult your healthcare provider to assess for secondary causes, verify proper administration technique, and consider dose optimization or alternative treatment strategies

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Negro R, Greek G, Mangieri T, Pezzarossa A, Dazzi D, Hassan H

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Motor and Perceptual Recovery in Adult Patients with Mild Intellectual Disability

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