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(3) This potential mechanism and further studies are described below

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Results showed that NaF caused elevation in liver TBARS and nitric oxide (NO), and reduction in superoxide dismutase (SOD), catalase (CAT), total antioxidant capacity (TAC) and glutathione (GSH)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 101.Wiley D.C., Skehel J.J

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Other symptoms found in patients with -glutamylcysteine synthetase deficiency are transient jaundice, reticulocytosis, and hepatosplenomegaly

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doi: 10.1111/j.1399-3054.2008.01193.x

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A 2025 review in the Journal of Translational Medicine (PMID: 39980008 ) confirmed that this energy deficit directly reduces oocyte quality, impairs follicle development, and accelerates ovarian reserve loss

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