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(3) This potential mechanism and further studies are described below

Results showed that NaF caused elevation in liver TBARS and nitric oxide (NO), and reduction in superoxide dismutase (SOD), catalase (CAT), total antioxidant capacity (TAC) and glutathione (GSH)

[DOI] [PMC free article] [PubMed] [Google Scholar] 101.Wiley D.C., Skehel J.J

Other symptoms found in patients with -glutamylcysteine synthetase deficiency are transient jaundice, reticulocytosis, and hepatosplenomegaly

doi: 10.1111/j.1399-3054.2008.01193.x

A 2025 review in the Journal of Translational Medicine (PMID: 39980008 ) confirmed that this energy deficit directly reduces oocyte quality, impairs follicle development, and accelerates ovarian reserve loss
