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All of these studies were randomized trials with either mouse model or hamster model

Similarly to the analysis of fluoroquinolone-induced tendinopathy, patients diagnosed with tendinopathy or receiving dexamethasone during the first 0- to 5-month run-in period were excluded from this analysis

PMC 2709701

However, recent findings, in particular in Caenorhabditis elegans but also in rodents, suggest that ROS generation is not the primary or initial cause of aging

Clinical evidence: The STEP (Semaglutide Treatment Effect in People with obesity) clinical trial program is the largest body of evidence supporting any weight loss medication

doi:10.1002/14651858.CD009318.pub2 [DOI] [PMC free article] [PubMed] [Google Scholar] 63.Zhou M, Chen N, He L, Yang M, Zhu C, Wu F