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FIGURE 2 Apoptosis and ATG are processes altered in cancer cells that show critical metabolic transformations associated with enhanced cellular stress

These compounds do not work through the same pathways

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doi: 10.3390/antiox11010154

In one sentence, the mechanism is receptor-mediated: GHRP binding to GHS-R1a activates a Gq/11-coupled phospholipase C cascade that mobilises intracellular calcium and triggers exocytosis of stored GH from the anterior pituitary, independent of hypothalamic GHRH signalling